Scientists find coronavirus patients most infectious in FIRST WEEK of symptoms
Research suggests that the virus replicates at its highest levels during the initial week of symptoms. The researchers was published in the science journal Nature.
Scientists from Berlin’s Charite Universitatsmedizin analysed the data from coronavirus patients.
They charted how infection they were and when based on how the virus spreads.
They also measured how much patients spread the virus through coughs.
Researchers looked at nine adults from Munich who had mild cases.
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They said: “Our initial results suggest that measures to contain viral spread should aim at droplet, rather than fomite-based, transmission (via objects or materials).
“The prolonged viral shedding in sputum is relevant not only for hospital infection control, but also for discharge management.
“In a situation characterised by limited capacity of hospital beds in infectious diseases wards, there is pressure for early discharge following treatment.
“Based on the present findings, early discharge with ensuing home isolation could be chosen for patients who are beyond day 10 of symptoms with less than 100,000 viral RNA copies per ml of sputum.
“Both criteria predict that there is little residual risk of infectivity, based on cell culture.”
The new study showed the results of analysis of throat and lung sample, as well as what the patients excreted.
High levels of virus replication occurred in upper respiratory tract tissue.
High viral shedding was also located in the upper respiratory tract.
The most this occurred was during the first signs of symptoms.
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The scientists isolated an infectious form of the virus.
Two of the patients showed early signs of pneumonia, and continued to shed high levels of the virus until day 11 of infection.
The virus remained detectable in phlegm after symptoms had stopped.
It wasn’t located in blood or urine samples.
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